I hate you people.....You start threads but you don't have the "balls" to actually "say' anything controversial yourself. However, you want people like me to say controversial things. OK! I WILL. I think Todd Putz is doing a good job. Put that in your pipe and smoke it!
I will let you start this:
Sir - I do think that your drug is excellent. The problem is you and your colleagues attitude. Its a bit too condescending - I think. Remember that old bible passage: Pride cometh before destruction. I'm not saying that this passage applies to you...but please re-read your comment and please understand how some may interpret this as a little bit "cocky".
I think TP is doing a great job. Thanks TP for leading us into "GLORY" . Trust me...we will get there.
Are you calling me an idiot - Dickwad!
Are you calling me an idiot - Dickwad!
Spoke to a couple of investigators in my area - they have had problems with the final analysis of the Phase 2 data. Each have had 2 patients with elevated ALT that they feel were caused by 5172. Both have said that the product is close to being dead. Flares at week 4 in each, all were discontinued but had coding issues so didn't show up in final presentation. Phase 3 except for renal study now on hold until the hepatic safety of 5172 is confirmed from other studies. Both PI told me that best case is that drug is now delayed from starting Phase 3 for 12-18 months. Worst case is that 5172 is done.
Spoke to a couple of investigators in my area - they have had problems with the final analysis of the Phase 2 data. Each have had 2 patients with elevated ALT that they feel were caused by 5172. Both have said that the product is close to being dead. Flares at week 4 in each, all were discontinued but had coding issues so didn't show up in final presentation. Phase 3 except for renal study now on hold until the hepatic safety of 5172 is confirmed from other studies. Both PI told me that best case is that drug is now delayed from starting Phase 3 for 12-18 months. Worst case is that 5172 is done.
I doubt this is true. Why would we push forward if there's safety problems?