Gilenya "WINNING"



















Oh good one. How many cases of PML I bet over 100 by the end of the month. How many dead. Avonex and Tysabri "LOSING"

100 cases doesn't seem like a big number. 100 cases out of how many patients?

Good one. I don't see you posting anything about regulatory approval of the test that lowers risk of PML.

Yeah, you're real objective. Keep worrying about your bonus and hoping for bad things, Negative Nancy.
 






100 cases doesn't seem like a big number. 100 cases out of how many patients?

Good one. I don't see you posting anything about regulatory approval of the test that lowers risk of PML.

Yeah, you're real objective. Keep worrying about your bonus and hoping for bad things, Negative Nancy.

This "test" is only available in Europe on a limited basis. There is a study in the US that only includes 9000 people. The study is being conducted over the course of two year. The FDA has not approved any test for everyone either taking Tysabri or for everyone that is currently being switched to Tysabri.

The test does not lower the risk of PML. The test identifies individuals that may be more apt to develop PML. Those individuals will likely not be approved to take Tysabri.

Overall the rate theoretically will go down - but it is only theoretical. It will be interesting to see the results. It may also be interesting to see in two years what other drugs in the pipeline that are waiting in the wings to replace the current treatments.
 






This "test" is only available in Europe on a limited basis. There is a study in the US that only includes 9000 people. The study is being conducted over the course of two year. The FDA has not approved any test for everyone either taking Tysabri or for everyone that is currently being switched to Tysabri.

The test does not lower the risk of PML. The test identifies individuals that may be more apt to develop PML. Those individuals will likely not be approved to take Tysabri.

Overall the rate theoretically will go down - but it is only theoretical. It will be interesting to see the results. It may also be interesting to see in two years what other drugs in the pipeline that are waiting in the wings to replace the current treatments.

It's called choice! Tysabri had changed people's lives and Gilenya will as well! Can't you just be happy that patients now have more choices or options. None of these drugs work 100%. Think about the pts that have failed on the platform therapies. I sell Gilenya and I am doing well. There is room for everyone.
 






It's called choice! Tysabri had changed people's lives and Gilenya will as well! Can't you just be happy that patients now have more choices or options. None of these drugs work 100%. Think about the pts that have failed on the platform therapies. I sell Gilenya and I am doing well. There is room for everyone.


I am happy for patients but many MS docs us Tysabri to make money that's wrong. How would you like a member of your family put on a drug so a doctor can fill a chair.
 






If it was improved in Europe, it obviously has shown something quite significant already.

And 9,000 patients sounds like a pretty huge number to me. I'd say this is great news for the benefit/risk of Tysabri.

You'll be a happier person if you find a way not to be negative about absolutely everything.
 






It's called choice! Tysabri had changed people's lives and Gilenya will as well! Can't you just be happy that patients now have more choices or options. None of these drugs work 100%. Think about the pts that have failed on the platform therapies. I sell Gilenya and I am doing well. There is room for everyone.

Of course it's called choice. I never said otherwise.

My reply was to the person that implied there is a test that is available to all potential candidates for Tysabri to determine their PML risk level and that simply is not true. It is undergoing testing.

I'm glad your sales are doing well. Again no one said otherwise.

My only point is that the testing will take two years (for FDA) and there is quite a bit in the pipeline that will be out within the next five. It will be interesting to see what happens then.
 






I am a patient who was on Tysabri for 2 years...tested positive for JV virus antibodies so I am switching to Gilenya. It is the better of the evils. Good luck on your bonus...
 






It's called choice! Tysabri had changed people's lives and Gilenya will as well! Can't you just be happy that patients now have more choices or options. None of these drugs work 100%. Think about the pts that have failed on the platform therapies. I sell Gilenya and I am doing well. There is room for everyone.

Sunshine, it is utterly amazing how you can twist almost everything a person writes on this board. Nowhere did Patient1 question a person's choice of what MS medication to take. He/she simply stated some facts about the JC virus test that is being researched yet there you are, rambling on about how a patient's choice is being questioned. You are obsessed with that and insert it into anyone questioning Tysabri. Please learn how to read what other people are saying and give us break!
 






Sunshine, it is utterly amazing how you can twist almost everything a person writes on this board. Nowhere did Patient1 question a person's choice of what MS medication to take. He/she simply stated some facts about the JC virus test that is being researched yet there you are, rambling on about how a patient's choice is being questioned. You are obsessed with that and insert it into anyone questioning Tysabri. Please learn how to read what other people are saying and give us break!

The person who posted that isn't your sunshine, lunatic.
 






If it was improved in Europe, it obviously has shown something quite significant already.

And 9,000 patients sounds like a pretty huge number to me. I'd say this is great news for the benefit/risk of Tysabri.

You'll be a happier person if you find a way not to be negative about absolutely everything.

Please - tell me how they "improved it" in Europe.

It is only available in Europe on a limited basis and the 9000 is not all patients. It is patients compared to a "normal" (and I use that term loosely for you) population.

No one said good news or bads news - simply objective fact.

And by the way I'm an incredibly happy person. You however are questionable since you seem to want to twist whatever anyone says to try and inflame and create idiotic argument with them.

Sorry - no time for such nonsense. As I said on many occasions, if I have something to say, I will. No more no less. Have a great day!
 


















Gilenya has a few more months left in it's life. Things are coming. Big things. And when they do, they will be packing their bags. Let their ship sink. Soon enough all will know the ugly that occurs with this awful drug.
 






Gilenya has a few more months left in it's life. Things are coming. Big things. And when they do, they will be packing their bags. Let their ship sink. Soon enough all will know the ugly that occurs with this awful drug.

Well, I don't things look all the rosy for Kilsabri. Here is part of a recent news release:

"Biogen Idec Inc. has halted enrollment in a large, long-term clinical trial aimed at testing the earlier use of multiple sclerosis drug Tysabri, citing a slower-than-expected pace of finding participants.

The Surpass study aims to test the effectiveness of Tysabri, sold with Elan Corp, when patients switched from more widely used drugs. Tysabri has proved to be highly effective; however, because of a link to a rare brain infection, the patients taking the drug tend to be those who have stopped responding to other drugs or have aggressive cases of MS.

The study started a year ago and had aimed to enroll 1,800 patients to be followed for about two years, yielding data in 2013 or 2014. Enrollment was stopped last month, but participating patients will continue in the trial.

Biogen spokeswoman Kate Weiss declined to comment on the number of patients enrolled, citing policy. The company has decided to devote its resources toward "risk stratification" efforts for the drug and remains dedicated to studying its effectiveness, she said."

Can't even get 1800 patients to enroll for a drug you guys keep preaching is so wonderful. The writing is on the wall, isn't it?