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Cancer drugmaker Agios offers promising data from two studies testing blood disorder drug

cafead

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  • cafead   Jun 12, 2020 at 11:13: AM
via With two cancer drugs on the market, the spotlight is on Agios’ rare metabolic disease franchise led by mitapivat, its experimental drug under development for a range of conditions including pyruvate kinase deficiency, thalassemia, and sickle cell disease.

At the European Hematology Association Annual Congress (EHA), the company issued two updates on the effect of mitapivat — a drug designed to target pyruvate kinase-R (PKR), an enzyme involved in the conversion of sugar, or glucose, into energy that is critical for the survival of red blood cells.

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