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See #1 above. That is true.   I can also tell you I think the job will be difficult but doable.  There are some good people there.  If you want the job go for it.  I work at Shire now and can honestly tell you there's people here who would work for Supernus if the opportunity presented itself.  If it doesn't work out at least you got pharma experience that you were looking for.  Update the resume and move on with more experience.  I do believe uou will be happy though unless you work for one of the handful of asshole RDs who will make your life miserable. But that is a risk and reality at any company. Good luck.