Stock price is not an indicator for lay-offs. Revenue declines YOY are. The reality of limited price increases to achieve "revenue growth" vs actual volume growth will show that Amgen is a no growth company. The game of using price increases to inflate revenue growth is over. Costs have been with AFP to fund the launch of new products (Repatha and Kyprolis) - both failures. Biosimilars of Neupogen/Neulasta are pending with uncertainty surrounding Enbrel biosimilars. With no revenue growth, the middle of the P&L will be cut to show a positive bottom line to the Street. That middle cut means layoffs in 2017 - unless the sales force can actually sell something.