Bam































R&D fat is where I would start. This company relies on external innovation. How much money could be redirected to acquisitions if the cost of useless R&D was cut. Ask what group is actually a good return on investment - keep them, outsource the rest and keep a few people for due diligence but not to do anything after the acquisition. Rely on the people who from the acquisition-see Allergan Aesthetics - that is working due to the ring fence except for cmc.
 












Poster above isn’t wrong about lack of internal innovation.

beyond inventing patent thickets, Abbott/vie doesn’t invent new stuff. this is a company that just buys other people’s stuff. At best they run a phase 3, but recently they just buy approved crap and lawyer it up.

nothing wrong with that, but they sunk a ton into r and d post split to try to prove they weren’t like Abbott. Time to liquidate all that stuff.
 






Poster above isn’t wrong about lack of internal innovation.

beyond inventing patent thickets, Abbott/vie doesn’t invent new stuff. this is a company that just buys other people’s stuff. At best they run a phase 3, but recently they just buy approved crap and lawyer it up.

nothing wrong with that, but they sunk a ton into r and d post split to try to prove they weren’t like Abbott. Time to liquidate all that stuff.
Buying stuff may work for a while, but it is not sustainable in the long term. Problem is, if you don't have some internal innovation, you make bad decisions on external innovation. Either that or you overpay. Whether it's manufacturing, clinical trials, or research/innovation, it is pretty hard to effectively outsource something if you are not already good it at yourself.
 






Buying stuff may work for a while, but it is not sustainable in the long term. Problem is, if you don't have some internal innovation, you make bad decisions on external innovation. Either that or you overpay. Whether it's manufacturing, clinical trials, or research/innovation, it is pretty hard to effectively outsource something if you are not already good it at yourself.
If they were good add it, why do they need to buy innovation?

If they could run phase 3s and register products, why the recent crl that puts off approval until 2024 according to earnings update?

This is not an R&D organization and nothing wrong with that. Be thankful for the financial means to buy innovation and provide on market support.
 






If they were good add it, why do they need to buy innovation?

If they could run phase 3s and register products, why the recent crl that puts off approval until 2024 according to earnings update?

This is not an R&D organization and nothing wrong with that. Be thankful for the financial means to buy innovation and provide on market support.
 






If they were good add it, why do they need to buy innovation?

If they could run phase 3s and register products, why the recent crl that puts off approval until 2024 according to earnings update?

This is not an R&D organization and nothing wrong with that. Be thankful for the financial means to buy innovation and provide on market support.
Time will tell if we can catch lightning in a bottle yet again.
 






Abbvie did pretty well after splitting from Abbott (very well if you base it on stock price since the split), but isn’t going to come close to what they said they could do: grow through and past humira LOE.

just imagine if the US patent thicket hadn’t held up? Things are tough now with upa and riza not making up the gap. Imagine it was 4 years ago and there was nothing to bridge the lost revenue? Abbvie would probably had been eaten by Pfizer and chopped into pieces for used parts.

The company will contract 20+% and then need to figure out what they want to be post Humira. Everyone is a player in immunology now and Abbvie is bush league when it comes to oncology R&D.

The panic merger with Allergan completely jumbled any strategy they had.

In other words buckle up and keep your head down!
 






If they were good add it, why do they need to buy innovation?

If they could run phase 3s and register products, why the recent crl that puts off approval until 2024 according to earnings update?

This is not an R&D organization and nothing wrong with that. Be thankful for the financial means to buy innovation and provide on market support.
I'm not saying you can't buy innovation, I'm saying you can't buy what you don't understand. The numbers speak volumes: Abbvie acquired BASF/Knoll for 6 billion and got Humira. No wait, ABBOTT acquired them, ABBVIE did the Allergan deal for 60 billion. Think something like Humira will come out of that?

This is a classic trust fund baby problem - your parents made one really good decision and you think that makes you a genius. Right now there's a lot out of crap for sale out there at low valuations, but even at a low price it's still crap. Will a trust fund baby be able to dig through all that crap to find the diamonds? We shall see.

Abbvie is clearly not an innovator, but it's also waaaay too early to proclaim they can buy their way out of this. I voted with my feet and money. Got out and sold at 165.
 






They did kinda ok, but in the end the Abbott zombies just kicked the can 10 years down the road.

abbott knew this would happen. The whole c suite has retired except Rick. The R&D wonderkind left.

The company will survive in a diminished state. Just kinda plod forward. After they extreme cost cuts murder some folks in the next 3 years.
 


















There is no luck in acquiring Humira, Skyrizi and Imbruvica. That is making right bets. That is sorting thru all the crap that could be bought and picking a winner. Same thing goes for the Allergan acquisition - you get Botox, vraylar, ubrelvy and qulipta for a bargain.

Abbott/AbbVie knows how to acquire products and maximizes the return on investment with excellent commercial execution. That is a fact.

Now Knoll, Pharmacyclics and Allergan, the ‘golden geese’ will never lay another egg now that they have shacked up with Abbott Park. They are or will be permanently sterilized as they learn to do things the AbbVie way. The scientists that came over from Knoll or Pharmacyclics - have they been able to produce anything with all the resources they could only dream about as standalone companies. No. That is fact. And the same will go for Allergan scientists. AbbVie does not an innovator culture. AbbVie leadership shoves their losing way down peoples throat, look exodus happening over the last year. You can’t be ultra risk averse and discover new first in class medicines. It’s an oxymoron. You also can’t have the incompetent R&D leadership that rules AbbVie.
 






There is no luck in acquiring Humira, Skyrizi and Imbruvica. That is making right bets. That is sorting thru all the crap that could be bought and picking a winner. Same thing goes for the Allergan acquisition - you get Botox, vraylar, ubrelvy and qulipta for a bargain.

Abbott/AbbVie knows how to acquire products and maximizes the return on investment with excellent commercial execution. That is a fact.

Now Knoll, Pharmacyclics and Allergan, the ‘golden geese’ will never lay another egg now that they have shacked up with Abbott Park. They are or will be permanently sterilized as they learn to do things the AbbVie way. The scientists that came over from Knoll or Pharmacyclics - have they been able to produce anything with all the resources they could only dream about as standalone companies. No. That is fact. And the same will go for Allergan scientists. AbbVie does not an innovator culture. AbbVie leadership shoves their losing way down peoples throat, look exodus happening over the last year. You can’t be ultra risk averse and discover new first in class medicines. It’s an oxymoron. You also can’t have the incompetent R&D leadership that rules AbbVie.
Fuck off. That is fact.
 






There is no luck in acquiring Humira, Skyrizi and Imbruvica. That is making right bets. That is sorting thru all the crap that could be bought and picking a winner. Same thing goes for the Allergan acquisition - you get Botox, vraylar, ubrelvy and qulipta for a bargain.

Abbott/AbbVie knows how to acquire products and maximizes the return on investment with excellent commercial execution. That is a fact.

Now Knoll, Pharmacyclics and Allergan, the ‘golden geese’ will never lay another egg now that they have shacked up with Abbott Park. They are or will be permanently sterilized as they learn to do things the AbbVie way. The scientists that came over from Knoll or Pharmacyclics - have they been able to produce anything with all the resources they could only dream about as standalone companies. No. That is fact. And the same will go for Allergan scientists. AbbVie does not an innovator culture. AbbVie leadership shoves their losing way down peoples throat, look exodus happening over the last year. You can’t be ultra risk averse and discover new first in class medicines. It’s an oxymoron. You also can’t have the incompetent R&D leadership that rules AbbVie.

Was Rova-T the right bet?

Allergan was 60 bil. That debt must feel nice with high interest rates. Time will tell if that was correct bet with Botox going off patent and aesthetics struggling.

Inflation reduction act now limits patent thickets on blockbusters.

it’s going to get real interesting. The ax is being sharpened big time.