Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting Dat

[Anonymous]

What’s the over/under on how long it will take before this is added to Statin labels? I say somewhere between five years and never depending on how much money pharma companies pay to suppress this information!

http://www.medsci.org/v12p0223.htm

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Good Grief.

"Results: In the FAERS database analyses, significant signals for colorectal cancer and pancreatic cancer were found for statins as a class. In the ESSA, significant associations between statin use and colorectal cancer and pancreatic cancer were found, with adjusted sequence ratios (95% confidence intervals) of 1.20 (1.08-1.34) and 1.31 (1.13-1.53), respectively, at an interval of 48 months."

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

I am sure we will get our new details pieces with this information in it soon so we can make sure physicians have the most up to date information on our product. After all that is why we are arguing for "free speech" and the ability to promote off label.

Bwaaahahahahaa I crack myself up.

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Interesting that this is a Japanese study since Crestor was created in Japan.


"Shionogi & Company, Limited (塩野義製薬株式会社 Shionogi Seiyaku Kabushiki Kaisha?) is a Japanese pharmaceutical company best known for developing Crestor."

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Means nothing. Crestor lowers C and LDL. What would you rather have, a little colon or pancreatic cancer, or C that out of control??? I thought so. Most patients would rather die than have high cholesterol! See, we are doing them a favor by killing them. It's all in how you look at it, and more importantly, is our bonus!

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Conclusion:

Multi-methodological approaches using different methodologies, algorithms, and databases suggest that statin use is associated with an increased risk for colorectal and pancreatic cancer.



And the AZ poster says, "good grief."

Eat healthy and exercise. Don't consume manufactured chemicals. Get a good night's sleep.

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Conclusion:

Multi-methodological approaches using different methodologies, algorithms, and databases suggest that statin use is associated with an increased risk for colorectal and pancreatic cancer.



And the AZ poster says, "good grief."

Eat healthy and exercise. Don't consume manufactured chemicals. Get a good night's sleep.

There is a new day coming that will change everything in the treatment of high cholesterol.
The first true biotech a new class of drug that will replace statin therapy has cleared the FDA. Crestor going generic was going to be a big enough financial hit, but this will totally eliminate the statin class of drugs. While AZ is promoting constipation relief, the real bio tech companies are creating a whole new class of drugs that will revolutionalize drug therapy.

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Who cares? Crestor goes generic next year if not sooner.

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Who cares? Crestor goes generic next year if not sooner.

Ahhhh, probably all the patients who develop cancer while on Statin. I personally know someone who died of pancreatic cancer and they were taking a statin. Time to call a lawyer.

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Ahhhh, probably all the patients who develop cancer while on Statin. I personally know someone who died of pancreatic cancer and they were taking a statin. Time to call a lawyer.

Are you referring to the anticancer properties of statins?

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703461/

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

http://www.webmd.com/colorectal-cancer/news/20140804/statins-may-aid-survival-from-colon-cancer

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Are you referring to the anticancer properties of statins?

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703461/

Good Point. Lets take a know Pharma hoar's word for it so he can continue to line his pockets verses over a decade of actually AE reports. But wait, even he admits Stains have no effect on cancer!

"Conflicts of interest: Dr Chan has consulted for Bayer Healthcare, Millennium Pharmaceuticals, and Pfizer Inc.

Evidence from clinical studies is, however, conflicting.

Collectively, the influence of statin use on colorectal cancer in cardiovascular RCTs appears neutral. Taken together with the null observational analysis of statin use in the APC trial, this has certainly dampened enthusiasm for statins as chemopreventive agents.

From a clinical practice perspective, at present, there is insufficient evidence to recommend the use of statins for colorectal cancer chemoprevention."

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

Are you referring to the anticancer properties of statins?

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703461/

Typical Pharma Response. Takes a single positive Pharma sponsored study and ignores a dozen negative studies that refute those findings. If you look for it I am sure you will find a study that says cigarette smoking is actually good for you. It was probably written by the same guy who wrote the article you linked. We are on to you and your days of profiting through reckless and deceptive marketing practices at the expense of patient lives will soon be over.


http://www.ncbi.nlm.nih.gov/pubmed/17687150/

 

[Anonymous]

Re: Association between Statin Use and Cancer: Data Mining of a Spontaneous Reporting

There is a new day coming that will change everything in the treatment of high cholesterol.
The first true biotech a new class of drug that will replace statin therapy has cleared the FDA. Crestor going generic was going to be a big enough financial hit, but this will totally eliminate the statin class of drugs. While AZ is promoting constipation relief, the real bio tech companies are creating a whole new class of drugs that will revolutionalize drug therapy.

True enough. Crestor is gone next year anyway, along with the "why do we need it anyway", XR. Soon after that, Symbicort will be gone too. So what does AZ do? They team up with anyone they find hoping that by throwing enough shit on the wall that some will stick. Frenchie spends most of his time at his stylist dyeing his hair. Now that Pfizer offer of $120 billion, that Frenchie turned down, looks pretty damn good in hindsight! All of the major stockholders must be singing a sad song of regret for not pushing to take the offer.