As developers work on cracking KRAS, Germany's Boehringer has quietly begun testing...

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via For decades, scientists scratched their heads about KRAS, the notorious cancer-causing protein. Its smooth terrain long eluded manipulation, largely due to the absence of a distinct pocket for a drug to latch on to. However, the process of trial and error finally yielded progress — triggering a flock of companies, including Amgen, J&J, Merck, and AstraZeneca, to engineer compounds designed to annex the oft’ mutated oncogene. And now, it looks like Germany’s Boehringer Ingelheim has officially entered the fold.

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