Amgen wants to become an immuno-oncology/hem onc leader

Anonymous

Guest
But they aren't. They are late to the game and no one sees Amgen as a leader. THIS IS AFFIRMED BY AZ CHOOSING CELGENE AND NOT AMGEN!!!

http://finance.yahoo.com/news/astrazeneca-insists-celgene-deal-strategy-104649996.html

LONDON (Reuters) - AstraZeneca (AZN.L) is getting a $450 million (297.42 million pounds) windfall by letting Celgene (CELG.O) develop a prized immunotherapy drug for blood cancers but its chief executive insists the deal is about strategy, not cash.

Some investors are worried about the drugmaker's reliance on such "externalisation" deals to fill a short-term revenue gap. Deutsche Bank analyst Richard Parkers said income from these agreements was of "questionable sustainability".

Chief Executive Pascal Soriot, however, said he had been looking for a partner in blood cancers since last year and by teaming up with U.S.-based Celgene, a leader in haematology, AstraZeneca would accelerate its drug's path to market.

AstraZeneca will effectively give away around half the sales of its drug MEDI4736 in blood cancers under the Celgene agreement, but Soriot said the deal would unlock value that the British company could not have achieved on its own.

"We could do it ourselves but with a partner in haematology we will do much, much better," he told reporters in a conference call. "It's more strategically driven than financially driven, though of course the financial aspects also help."

AstraZeneca Inks Multiple Deals, Immuno-Oncology in Focus - Analyst Blog Zacks 3 hrs ago
Aberdeen retreats on sell advice Financial Times q 7 hrs ago
More
AstraZeneca believes blood cancers could represent 40 percent of the total cancer market, yet Soriot said it did not include this in a $45 billion 2023 sales forecast issued last year as it was not clear then how it would tap the market.

AstraZeneca has extensive experience in solid tumours, but not blood cancers, which is a highly specialised field involving different groups of doctors.

Citi analyst Andrew Baum said the Celgene collaboration made sense given AstraZeneca's absence of expertise and Celgene's desire to expand its presence in immuno-oncology (I-O).

AstraZeneca is up against several I-O rivals, such as Bristol-Myers Squibb (BMY.N), Merck (MRK.N) and Roche (ROG.VX), and Soriot argued that by getting into bed with Celgene it would be at a competitive advantage in the blood cancer space.

Under the deal, AstraZeneca will book sales of MEDI4736 in blood cancers and will pay Celgene an initial royalty of 70 percent, which will decrease to approximately half of sales over a period of four years.
 




Amgen is just mediocre!


Seattle biotech Juno Therapeutics is teaming up with British pharmaceutical company AstraZeneca to explore the potential of combining two of their drug products into one therapy. Under the new collaboration, the two companies will also co-fund a clinical trial together.
Juno (Nasdaq: JUNO) will work directly with MedImmune, the research and development arm of AstraZeneca (Nasdaq: AZN) to explore how well one of Juno's drug candidates works with a product from MedImmune with the goal of better understanding how those drugs work.
"We believe combination strategies such as this will help us better understand the full potential of our engineered T cell platform in both hematological and solid tumor settings," said Dr. Mark Frohlich, Juno's executive vice president of research and development.
Financial details of the collaboration were not disclosed.
A deal that will help foot the bill of a clinical trial is good news for Juno, which plans to burn through about $150 million in cash this year. The company also has a long way to go before it will bring a product to market.
Juno develops immunotherapy treatments for cancer. Immunotherapy involves drawing blood from a patient, engineering those cells to better fight cancer and then infusing them back into the patient. The concept relies on boosting the patient's immune system to battle the disease on its own.
Juno has a lot of plans for 2015 and recently scooped up a new headquarters to prepare for an expansion. While Juno has focused on treatment of blood cancers so far, is also exploring the effectiveness of its drug candidates in solid tumors.