Gilead's CD47 clinical hold expands as CEO O'Day expresses 'sense of urgency' in getting trials back on track

Gilead revealed that a partial clinical hold for its CD47 targeted cancer hopeful is larger than originally thought.

Last week, the California-based biotech shared that a handful of trials for magrolimab in combination with azacytidine had been placed on a partial clinical hold because of an “apparent imbalance” in adverse reactions seen in the study arms. The hold applied to five studies, ranging from early- to late-stage development for myelodysplastic syndrome (MDS), acute myeloid leukemia and myeloid malignancies, including the phase 3 Enhance trials.