Tough to calculate bc they have 20 distributors along with 51 direct reps. Generally speaking...Avance sales make up approx. 65% of total revenue. Let's say direct reps were responsible for $33mil in sales out of the $41mil in total sales for 2016. Looking at the $33mil sales breakdown...$19mil is Avance sales and $14mil is Axoguard sales. $19mil/51 direct reps= $372k Avance sales/rep and $274k/Axoguard sales/rep. In conclusion, direct reps average about $650k in total sales. Key expenses that are causing Axogen to lose money are prof education courses, high rep turnover, shipping expenses (avance has to ship on dry ice in heavy coolers) and high officer pay.