Dr. Carl June's drugmaker scraps lead CAR-T program after 2 trial participants die

Tmunity, a clinical stage biotherapeutics company, said it is abandoning its lead program after two trial participants died due to neurotoxicity, Endpoints News reported June 2.

Tmunity was founded in 2015 by Oz Azam, MD, and Carl June, MD, the famed immunologist who pioneered T-cell therapies for cancer. Both physicians worked on CAR-T cell initiatives at Novartis before creating Tmunity, a spinout from the Philadelphia-based University of Pennsylvania.