Takeda and Ovid Therapeutics Expand Clinical Program for TAK-935/OV935 with New Studies in Rare Developmental and Epileptic Encephalopathies (DEE)

Takeda and Ovid Therapeutics Expand Clinical Program for TAK-935/OV935 with New Studies in Rare Developmental and Epileptic Encephalopathies (DEE)

Source: 
CP Wire
snippet: 
  • TAK-935/OV935 is a first-in-class inhibitor of the enzyme cholesterol 24-hydroxylase
  • TAK-935/OV935 may potentially treat rare epilepsies by inhibiting CH24H to decrease 24HC levels
  • In previous Ph I trial TAK-935/OV935 reduced 24HC levels between 47 and 63 percent