Genentech turns out lights at first commercial biologics plant, laying off 265 staffers

It’s the end of an era as the world’s first commercial biologics plant—once home to a secretive project dubbed “Orange Marmalade”—turns out the lights.

After years of planning, Genentech is winding down operations at its production facility in South San Francisco, the company told Fierce Pharma. The site wrapped up its final production runs several weeks back and is now in the decommissioning phase, which will take some six to 12 months.