CymaBay Therapeutics Reports Positive Results from Ph II Study of Seladelpar in Patients with Primary Biliary Cholangitis

CymaBay Therapeutics Reports Positive Results from Ph II Study of Seladelpar in Patients with Primary Biliary Cholangitis

Source: 
CP Wire
snippet: 
  • At 52 weeks, the mean decreases in alkaline phosphatase were -47% and -46% in the 5/10 and 10 mg groups
  • After 26 weeks, the median changes in the pruritus visual analog scale (VAS) was -50% and -55% in the 5 /10 and 10 mg groups
  • The company has ongoing Ph IIb trials of seladelpar in NASH