Adding a 'switch' to Cas9 to make CRISPR gene editing safer

Adding a 'switch' to Cas9 to make CRISPR gene editing safer

Source: 
Fierce Biotech
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One big challenge facing the development of CRISPR gene editing for use in humans is the fear that the Cas9 "scissors" used in the technology could cause unintended off-target effects. Researchers at the University of California, Berkeley, have come up with a potential solution: a “switch” mechanism that could keep the Cas9 enzyme turned off until it reaches its target site.