Xarelto Rebound Strokes

Discussion in 'Janssen' started by Anonymous, Sep 27, 2012 at 8:21 AM.

  1. Anonymous

    Anonymous Guest

    I just had my first rebound stroke has anyone else seen this in their territory? What are you telling the doc? I said we had a black box warning for this and he was pissed please serious replies only
     
  2. Anonymous

    Anonymous Guest

    I told him to box out more.
     
  3. Anonymous

    Anonymous Guest

    Yet another BI douche who'd rather post here than try to defend his/her downwardly-spiraling market share.
     
  4. Anonymous

    Anonymous Guest

    The black box isn't for rebound strokes. You are a complete idiot.
     
  5. Anonymous

    Anonymous Guest

    It explicitly states it is, can you not read??
     
  6. Anonymous

    Anonymous Guest

    "DiscontinUing Xarelto in Patients WitH nonValVUlar atrial fibrillation
    Discontinuing Xarelto places patients at an increased risk of thrombotic events. if anticoagulation with Xarelto must be discontinued for a reason other than pathological bleeding, consider administering another anticoagulant"

    ...not so much
     
  7. Anonymous

    Anonymous Guest

    consider getting us new product managers that can develop strategies for patients. duh.
     
  8. Anonymous

    Anonymous Guest

    DATA ??????????????????????????????????????????????
     
  9. Anonymous

    Anonymous Guest

    From Heart.org your product will kill more that it saves

    In addition to concerns about warfarin dosing, the FDA review questions the 20-mg once-daily dosing of rivaroxaban, saying the evidence supporting the rationale for evaluating the dose is not strong. In addition, the FDA is troubled by the rebound effect that occurs when patients stop taking rivaroxaban and the sponsor's proposed label instructions for the transition from rivaroxaban to warfarin. The review notes there were an excessive number of strokes in the rivaroxaban arm when the patients were transitioned from the blinded study drug to warfarin at the end of the study

    The BI DOUCHE
     
  10. Anonymous

    Anonymous Guest

    Nothing like creating drama elsewhere when you obviously have not idea how to handle your own drama over there at BI. Go crawl back under your rock!
     
  11. Anonymous

    Anonymous Guest

    I am trying to save lives this crappy product will kill people. Its built on lies crappy efficacy horrible bleed profile and rebound strokes. Shame on you JNJ.

    The BI DOUCHE
     
  12. Anonymous

    Anonymous Guest

    wow, thank God the world has you!!!! BTW, have you checked your own PI lately? Take a look at the Warning section
     
  13. Anonymous

    Anonymous Guest

    What the hell do you expect will happen to a patient if they discontinue ANY anticoagulant and they don't have a bridging option in place???? You think this "resumption" (or, the misnomer of "rebound") for increased stroke risk only applies to Xarelto? So what happens to a patient on Dabi who discontinues therapy (for whatever reason) with NO backup anticoagulant in place???? They mysteriously are cured of their stroke risk?

    Basic logic, pal.
     
  14. Anonymous

    Anonymous Guest

    See that is the JNJ lie, they didn't stop taking anticoagulants all together they were switched to another product. Which happens all the time in real life. As managed care coverage and cost will cause patients to bounce to different meds they can't do it with this product due to rebound stroke. What is scary is you are selling this product and you don't understand your own PI. Wonder how many people you have killed by your lack of knowledge. These products are no joke and you need to be honest with your customers.
     
  15. Anonymous

    Anonymous Guest

    Agreed, AC's are no joke...

    Who's ad's are all over the airwaves for 800-BAD-DRUG???!!!
     
  16. Anonymous

    Anonymous Guest

    +1
     
  17. Anonymous

    Anonymous Guest

    OMG you are an idiot and clearly have NO understanding what-so-ever of anticoagulation. You need some training dude. EVERY healthcare professional understands the need for bridging. EVERY healthcare professional understands how Coumadin works. You obviously do not. I am so glad you are my competition.
     
  18. Anonymous

    Anonymous Guest

    +2
     
  19. Anonymous

    Anonymous Guest

    Yes, I can see your point.
    Then, 1+2 = 3
     

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