Repatha Price Increase Coming

with outcomes on the horizon we are going to raise the price. I heard 5%. I don't think it's the best move for us

 

Praluent wins stay so we will go back to kicking your ass.

 

Good now that Praluent won the stay raise the price so we can go back to kicking your ass!!

 

The outcomes data barely met the PE, it is no where near what a payor would want or demand and the economics for reduction in CV mortality don't work, based on internal estimates rebates would need to be close to 60% to get access, the data while it met is PE was not what was hoped for. The team has been working furiously to mold the story for ACC to try and polish the result, if it were that good we would have gone public immediately, expect lower revenue, more reductions and more unrealistic expectations- SB

 

The outcomes data barely met the PE, it is no where near what a payor would want or demand and the economics for reduction in CV mortality don't work, based on internal estimates rebates would need to be close to 60% to get access, the data while it met is PE was not what was hoped for. The team has been working furiously to mold the story for ACC to try and polish the result, if it were that good we would have gone public immediately, expect lower revenue, more reductions and more unrealistic expectations- SB

 

Yes my house did not sell for $700K so I raised it to a million.

 

What percent reduction is needed to meet primary endpoints? I thought haven't announced that data yet

 

Trial was powered to hit a 15% difference. Given the price, a 30%+ likely needed for access without dropping price.

 

Treating high cholesterol is a lifetime condition. Even at a 15% reduction over a 5 year period, those numbers compound as the years/decades go by as evidenced by Statin studies.

Is the high cost due to production or simply recouping R&D costs?

 

Neither. It is for executive bonuses.

 

Neither of those it was based on pralulent. They hit market first and set price amgen could have discounted a bit butvwas greedy too, total development was 2.2B, so long journeyvto get money back, the right price would have been around 7500 annually with rebates in teens. The economics work for payer and amgen but they are greedy as always and put it on sales force, - SB

 

Can you spell monopoly... MONOPOLY. This is Amgen's soon to be sweet spot. Watch the price to increase and then some selective contracting/deals. Its the good old single source product days with Epogen and Neupogen! Happy days are here again!!!

 

These are number of events buddy not a LDL level percent.

 

$2.2B does not count the time factor of money to get back to positive ROI.

Fair pricing for amgen should be in the 4500-6000k tops.

Sanofi is incompetent but Amgen is greedy. Sean Harper is too arrogant to not think that payers and providers think the drug is overpriced without significant outcomes.

The ACC presentation will show who is right.

 

I'm aware, still believe the percent reduction of events vs baseline should increase the longer the time period.

 

The number was 18%, beat PE but doesn't touch the economic challenge. Do you think for a moment if there was a truly profound effect we'd be waiting to share? We've waited two years for outcomes andnnow have but won't share. The purpose of ACC is to tell the story of why 18% matters and should be sufficient to strong arm payors. Not to mention some of the unexpected untoward observed AE's that were not expected. Here we come neurocognitove impairment, - SB

 

Sean Harper will be complain of how irresponsible payers to block access for what THEY PERCEIVE as limited benefit. Amgen will be arrogant and try to frame the payers as blocking access to what Amgen believes is a monumental shift in the treatment paradigm. It's not bad drug, and 18% is showing clinical outcomes but Amgen is arrogant in that they want full access at a very high price. How many of you would buy a $100k Chevy Malibu or even a Toyota Camry....They may be good cars, just like Repatha is a decent drug, but not at that price. Amgen is a weird company that somehow forgets that it's product is only as good as your customers perceive it to be.

 

It wasn't 18%. It was only slightly over 10% unless you are talking about a sub pop

 

That would be a 1,400 dollar increase. Inflation was only 2.1 percent in 2016.

 

My manager is all about lower is better. Your body doesn't need cholesterol in the brain. Single digit is great. Amgen is great and cholesterol is bad. In fact, your body doesn't need any cholesterol at all. This person must be self injecting Repatha and experiencing some neurocognitve impairment as a side effect.

This person should start reading some non Amgen sponsored answers. As a sales rep, we need to think for ourselves and stop believing the brain wash messages. This is such an unethical company to allow a manager to keep selling this to the reps.

https://www.ncbi.nlm.nih.gov/m/pubmed/18757771/