There is still a legacy Schering BACE inhibitor in the clinic. Let's hope it's just verubecestat sucks but not the BACE mechanism
Full credit to Merck for testing this hypothesis and taking a really good BACE into the clinic. Sadly this is yet another example the the entire amyloid hypothesis is incorrect. BACE inhibition doesn't work, Gama-secretase inhibition doesn't work and antibodies don't work! Time for a significant re-think and always remember 'key opinion-leaders' only have 'opinions', it doesn't make them right!
hahaha!! this is great news! failure upon failure with downsizing coming soon! so great to read. you all have no idea how happy this makes me. serves you right too-you deserve all of this and much more